mesothelioma meaning

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mesothelioma meaning


Mesothelioma Stages
The stages of mesothelioma include stage 1 (cancer cells in one place), stage 2 (cancer cells entering lymph nodes), stage 3 (cancer cells spread to nearby organs and distant lymph nodes) and stage 4 (cancer cells spread throughout chest or abdominal cavity). Prognoses, survival rates and life expectancies decrease as stage number increases.
mesothelioma meaning

Cancer staging is a key part of mesothelioma diagnosis and treatment. Knowing how far the cancer has spread helps doctors decide which treatments to use. For example, doctors use cancer stage as a guideline when deciding whether a patient is likely to benefit from surgery.
Early-stage patients may benefit from surgery by living longer and experiencing fewer symptoms. Late-stage patients benefit more from treatment focused on symptom management. The goal of treatment in all stages is to improve quality of life and help people live longer.
Because mesothelioma symptoms don’t develop until later stages, most patients are not diagnosed until stage 3 or 4. The cancer’s cell type and the patient’s overall health also affect treatment options.
The most common treatment for mesothelioma is chemotherapy. Some patients get diagnosed early enough to qualify for surgery. Surgery is often combined with chemotherapy and radiation therapy to kill more cancer cells. Clinical trials are testing new therapies such as immunotherapy.
Stages of Mesothelioma
The stages of pleural mesothelioma are based upon the size of tumors and how far they have spread. The location and size of tumors has a direct impact on the symptoms a person may feel.
Tumor size and location also determines whether a person can undergo surgery. Unfortunately, surgery is no longer an option when tumors become too big or spread too far.
Stage 1
Initially, tumor growth is within a single area. The life expectancy of stage 1 mesothelioma is significantly better than later stages. It is difficult to catch the cancer this early because people with this stage do not usually experience symptoms.
Major surgery to remove the cancer is the first line of treatment. Doctors usually recommend an aggressive multimodal approach including surgery, chemotherapy, radiation therapy or immunotherapy.
Median life expectancy at stage 1 is 22.2 months with surgery.
Stage 2
Stage 2 symptoms are vague and mild, and patients and doctors often mistake them for signs of other illnesses such as the flu.
The available treatment options are generally the same as for stage 1 mesothelioma. Median life expectancy at stage 2 is 20 months with surgery.
Stage 3
Once the cancer progresses to stage 3, it may have spread to several tissues, organs and lymph nodes in the same region of the body where it formed.
Pleural mesothelioma patients may have difficulty breathing and chest pain even when resting. Discomfort may be felt in other parts of the body as well.
Some stage 3 cancer patients are ineligible for surgery and other aggressive treatments. At that point, doctors offer palliative options.
Median life expectancy at stage 3 is 17.9 months with surgery.
Stage 4
By stage 4, cancer has spread to other parts of the body. Cancer could be present in the liver, brain, bones or elsewhere. Patients may experience extreme difficulty breathing and swallowing, digestive problems and severe pain.
For stage 4 patients, doctors typically fall back on palliative treatments designed to ease pain and control other symptoms. Most stage 4 patients do not qualify for surgery.
Median life expectancy at stage 4 is 14.9 months or less with or without surgery.


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